Obeticholic Acid  Intermediate 3 : (E)-3A-HYDROXY-6-ETHYLIDENE-7-KETO-5 B -CHOLAN-24-0IC ACID CAS number is 1516887-33-4 ,We also call this the obeticholic intermediate OB-3. We conducted a comprehensive study of the intermediate Obeticholic Acid  Intermediate,and were able to provide several of its intermediates. we have conducted a positioning analysis on the corresponding impurities , done a full set of NMR, IR,HPLC. As the current market demand for Obeticholic intermediate 3 is relatively small, we accept personalized customization services with favorably prices. We look forward to conducting further discussions and communication with the buyer on the quality of Obeticholic intermediate 3. We strongly hope that our products continue to improve the quality and become your most reliable long-term partners!

Thera. Category:  Cholestatic liver disease

Cas No.: 1516887-33-4

Synonym:  (E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid;Obeticholic Acid-G; 

Molecular Formula:C26H40O4

Molecular Weight: 416.5934

Purity: ≥98.%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Obeticholic acid (Obeticholic Acid), also known as 6-ethyl chenodeoxycholic acid, is a new derivative of chenodeoxycholic acid (CDCA) in the primary bile acid, and a natural ligand for the farneside derivatives X receptor ( FXR). Oberbetaine is an agonist for farnesol X receptor, inhibiting gene expression of cytochrome 7A1 (CYP7A1) by activating the farnesol X receptor. Because CYP7A1 is the rate-limiting enzyme for biosynthesis of cholic acid, it can inhibit cholic acid synthesis and is useful in the treatment of primary biliary cirrhosis and nonalcoholic fatty liver disease.

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(E)-3A-HYDROXY-6-ETHYLIDENE-7-KETO-5 B -CHOLAN-24-0IC ACID  CAS number  1516887-33-4