Nintedanib (BIBF 1120) CAS 656247-17-5 is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, as well as an orally bioavailable, indolinone-derived, receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. We can offer Nintedanib CAS NO 656247-17-5 range from gram grade and kilogram grade. Our pure and accurate Nintedanib (BIBF-1120) is in high demand by our customers and can be availed at industry leading prices.
Thera. Category: Anti-Cardiovascular
Cas No.: 656247-17-5
Synonym: Intedanib;Vargatef;Nintedanib;Nintedanib (BIBF 1120);Nintedanib/Intedanib/Vargatef;Intedanib Vargatef;methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120);Vargatef (nintedanib)
Molecular Formula: C31H33N5O4
Formula Weight: 539.62482
Assay: ≥99.%
Packing: Export worthy packing
lMaterial Safety Data Sheet: Available on request
Usage:
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM which is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF) and along with other medications for some types of non-small-cell lung cancer.
Related Production:
CAS 656247-17-5, Intedanib
CAS 100-15-2, N-Methyl-4-nitroaniline
CAS 14192-26-8, Methyl 2-oxoindole-6-carboxylate
CAS 2653-16-9, 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
CAS 23543-31-9, 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide
CAS 262368-30-9, N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
CAS 1139453-98-7, N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
CAS 1160293-27-5, 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
CAS 1168150-46-6, (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester